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KMID : 0380020080230060529
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Korean Journal of Biotechnology and Bioengineering
2008 Volume.23 No. 6 p.529 ~ p.534
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Supercritical Extraction of Oriental Herb : Anti-aging and Anti-wrinkle Effects
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Abstract
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The reactive oxygen species generated by ultraviolet rays causes various types of cutaneous damage, such as lipid peroxidation and denaturation of the extra-cellular matrix. The accumulation of such damage contributes to skin aging, especially the formation of wrinkles. This study was carried out to develop functional cosmatic by using Oriental herb supercritical extracts (OHSE) for prevention of skin. Effects of OHSE on anti-oxidation, collagenase inhibition and collagen synthesis in normal human fibroblast were investigated. OHSE showed antioxidative activity as high as vitamin C, trolox and DL-penicillamine. Also OHSE showed promotive effect on collagen synthesis and inhibitory effect on collagenase activity. From this results, we conclude that OHSE may have the potential to be conveniently used as an additive in cosmetics for prevention and improvement of skin aging.
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KEYWORD
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Oriental Herb, supercritical extract, anti-wrinkle, anti-oxidation, collagen synthesis
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